correlation of random urinary protein to creatinine ratio in 24-hour urine samples of pregnant women with preeclampsia.
نویسندگان
چکیده
objective: to determine the value of random urinary protein to creatinine ratio (upcr) for diagnosis of proteinuria in pregnant women with preeclampsia. preeclampsia is the most common complication of pregnancy and one of the main causes of maternal mortality. so, early diagnosis of preeclampsia is very important. materials and methods: in this cross-sectional study 66 pregnant women suspected preeclampsia at ≥24 week of gestational age and bp ≥ 140/90 mm/hg were checked by two urine samples of 10am and 4pm to determine random upcr, as well as a 24-hour urine sample to evaluate 24-hour protein excretion. results: the result revealed that 74.2% of the studied population had significant proteinuria. there was a correlation between upcr and 24-hour urine protein excretion. pearson's correlation coefficient was 0.502 at 10am and 0.428 at 4pm. the best cutoff for the random urine protein to creatinine ratio at 10am was 0.470 with sensitivity and specificity equal to 87.5% and 84.2%, respectively. the best cutoff for the random upcr at 4pm was 0.595 with sensitivity and specificity equal to 91.7% and 94.7%, respectively. conclusion: result of 24-hour urine collection showing random upcr is considered as an appropriate situated method for emergency time.
منابع مشابه
Correlation of Random Urinary Protein to Creatinine Ratio in 24-Hour Urine Samples of Pregnant Women with Preeclampsia
OBJECTIVE To determine the value of random urinary protein to creatinine ratio (UPCR) for diagnosis of proteinuria in pregnant women with preeclampsia. Preeclampsia is the most common complication of pregnancy and one of the main causes of maternal mortality. So, early diagnosis of preeclampsia is very important. MATERIALS AND METHODS In this cross-sectional study 66 pregnant women suspected ...
متن کاملA comparison of spot urine protein-creatinine ratio with 24-hour urine protein excretion in women with preeclampsia.
INTRODUCTION Proteinuria is an important diagnostic component of preeclampsia. We prospectively compared the results of spot urine protein-creatinine (P/C) ratio with 24-hour urine protein excretion in women with preeclampsia. MATERIALS AND METHODS A total of 81 pregnant women with preeclampsia were prospectively studied for proteinuria. Urine P/C ratio was determined in a spot mid-stream uri...
متن کاملcorrelation of 2 hour, 4 hour, 8 hour and 12 hour urine protein with 24 hour urinary protein in preeclampsia.
objective: to find shortest and reliable time period of urine collection for determination of proteinuria. materials and methods: it is a prospective study carried out on 125 pregnant women with preeclampsia after 20 weeks of gestation having urine albumin >1 using dipstick test. urine was collected in five different time intervals in colors labeled containers with the assistance of nursing sta...
متن کاملCorrelation of 2 Hour, 4 Hour, 8 Hour and 12 Hour Urine Protein with 24 Hour Urinary Protein in Preeclampsia
OBJECTIVE To find shortest and reliable time period of urine collection for determination of proteinuria. MATERIALS AND METHODS It is a prospective study carried out on 125 pregnant women with preeclampsia after 20 weeks of gestation having urine albumin >1 using dipstick test. Urine was collected in five different time intervals in colors labeled containers with the assistance of nursing sta...
متن کاملCorrelation versus agreement; protein/creatinine ratio in spot urine and 24-hour urine protein.
Montero et al. do report the 95% limits on the Bland-Altman plot, perhaps the authors could have reported the 95% limits of agreement for a specific number of thresholds of proteinuria for example <300mg, <3.5 grams or >3.5 grams individually which would be useful for clini-cians trying to interpret spot urine pro-tein/creatinine ratio. I worry that readers of this excellent study may be left f...
متن کاملCorrelation between the protein/creatinine ratio in spot urine and 24-hour urine protein.
INTRODUCTION Measurement of the protein content in a 24-hour urine sample is the definitive method of establishing the presence of abnormal proteinuria. However, the urine collection is cumbersome. The spot urine protein to creatinine ratio seems to be a reliable diagnostic tool for urine protein measurement. OBJECTIVE Our aim was to evaluate the spot urine protein/creatinine ratio against 24...
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عنوان ژورنال:
journal of family and reproductive healthجلد ۷، شماره ۲، صفحات ۹۵-۱۰۱
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